Human hypoxic pulmonary vasoconstriction is unaltered by 8 h of preceding isocapnic hyperoxia
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چکیده
منابع مشابه
Human hypoxic pulmonary vasoconstriction is unaltered by 8 h of preceding isocapnic hyperoxia
Exposure to sustained hypoxia of 8 h duration increases the sensitivity of the pulmonary vasculature to acute hypoxia, but it is not known whether exposure to sustained hyperoxia affects human pulmonary vascular control. We hypothesized that exposure to 8 h of hyperoxia would diminish the hypoxic pulmonary vasoconstriction (HPV) that occurs in response to a brief exposure to hypoxia. Eleven hea...
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Hypoxic pulmonary vasoconstriction is a local reflex in the lung that diverts blood away from poorly oxygenated regions. Improvements in understanding of modulators of this response have led to pharmacologic methods whereby V/Q matching may potentially be improved in certain types of pulmonary pathology and during anesthesia for thoracic surgical procedures.
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ژورنال
عنوان ژورنال: Physiological Reports
سال: 2017
ISSN: 2051-817X
DOI: 10.14814/phy2.13396